Researchers at the University of Georgia have developed a new hand-sanitizing gel called NORel (Nitric Oxide Releasing gel), recently described in the journal Biomaterials Science. Unlike traditional alcohol-based sanitizers, which evaporate quickly and lose effectiveness within an hour, this innovative formula provides protection that lasts far longer—while also being gentle on the skin.
Extended and Effective Protection
In laboratory studies on rabbit skin, NORel eliminated more than 97% of harmful microbes, including Escherichia coli, Staphylococcus aureus (even drug-resistant strains), and Candida albicans. The results matched those of standard sanitizers containing about 62% ethanol, but with one major advantage: NORel’s antimicrobial action lasted up to two hours, well beyond the 30 to 60 minutes offered by alcohol gels.
Gentle on Skin
Frequent use of alcohol sanitizers often causes dryness and irritation. NORel is designed differently. It combines moisturizing ingredients such as glycerin and tea tree oil, along with a small amount of ethanol, to keep skin hydrated. Tests showed that the gel is cytocompatible, meaning it does not harm mammalian cells. In fact, it supported healthier cell growth compared to traditional gels, making it safer for repeated daily use.
The Role of Nitric Oxide
NORel’s effectiveness comes from nitric oxide (NO), a natural molecule in the human body that helps defend against infection. The gel releases NO gradually, providing sustained antimicrobial activity while avoiding microbial resistance—a problem often linked with overuse of conventional products.
Looking Ahead
This new sanitizer could prove especially useful in hospitals and care facilities, where hand hygiene is critical but skin irritation from constant cleaning is common. By combining extended protection with moisturizing benefits, NORel offers a promising next step in safe and effective hand hygiene.
Article source by Industrytap.com
Image source by Devyn Holman on Unsplash
